|
Vanessa I. Scanga, M.Sc. v.scanga@utoronto.ca Project Bio Adult neural stem cells and axonal regeneration following damage to the nervous system: an in vitro analysis Damage to the CNS results in disruption of the cellular matrix, persistence of an environment that is inhospitable to cell survival and loss of axonal guidance cues, ultimately resulting in an inability to repair the damaged tissue. We are exploring the possibility of utilizing combination strategies, focusing on the use of neural stem cells and tissue engineering to promote regeneration. We are currently developing in vitro assays as a first step towards the creation of a tubular implant to serve as a delivery vehicle for both neural stem cells and growth factors following spinal cord injury. Polymer screening using neural stem cell survival, migration and differentiation assays will enable the identification of materials and specific stem cell populations that will support and facilitate tissue repair and functional recovery following CNS injury. Employment and Education M.Sc. in Growth and Development Program Honours B.Sc. Awards Crothers |
|