Jiao Lu, M.Sc.
jiao.lu@utoronto.ca
Project Bio
Tradition chemotherapy results in massive damage in tumor cells as well as healthy ones. One of the goals in Molly's group is to develop a drug delivery system that targets specific cancer cells with minimum damage to the healthy tissue.
A strategy of doing so is to encapsulate anti-cancer drugs inside polymer nanoparticles, followed by modifying these self-assembled particles with antibodies that recognize specific markers expressed on the tumor cells. Click chemistry has been recognized as an exceedingly useful bioconjugation procedure and will be applied to this nanoparticle modification.
Employment and Education
Major in Chemistry
Minor in Biochemistry
Simon Fraser University, 2006
AnorMED, Medicinal Lab
May - Dec 2005, Research Assistant
May 2006 - Aug 2006
Prepare novel compounds in the drug development
program, tartgeting CCR5 chemokine recptor for the
treatment
of HIV
Supervisors: Dr. Ernest McEachern, Dr. Elyse Bourque, Dr. Krystina Vocadlo
May - March 2004
Simon Fraser University,
Department of Chemistry
Research Assistant
Working on the project of making a library of moth pheromone
analogs under the direct supervision of Dr. E. Plettner. Synthesize
and purify the precursors for gypsy moth pheromone analogs and analyze
with GC, GCMS, IR and NMR
Supervisor: Dr. Erick Plattner
Jan - Aug 2003
Simon Fraser University, Deparment of Biological Science
Research Assistant
Working on the project of identification and characterization
of genese involved in vascular development in Arabidopsis thaliana
Supervisor: Dr. Jim Mattsson.
